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When the medication is first introduced into your system, it begins interacting with receptors in the brain that influence appetite, but these pathways take time to adjust
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Your doctor or nurse will guide you on how to use the injection
This aspect could reflect an altered action of ghrelin on its specific receptors implicated in feedback mechanisms.83 Regarding the role of CCK in inhibiting food intake, CCK-A receptor knockout rats are hyperphagic and obese.84 In animals, as expected, repeated preprandial administration of CCK reduces food intake but it also increases meal frequency, with no resulting effect on body weight.85 Circulating levels of PYY are not elevated in obese individuals
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